腾冲市茨竹地铁多金属矿成矿地质特征及控矿因素

腾冲市茨竹地铁多金属矿现目前是一座正在开采的以磁铁矿为主、共（伴）生锡钨矿的小型矿山。为了增加矿山资源储量、延长矿山服务年限，通过对矿区的地质特征阐述和对矿区地层岩性、构造、岩体等控矿因素的分析研究，总结了矿区成矿规律并形成了矿区的成矿模式，为矿区深部探矿、外围找矿提供了一定的理论依据。     

Vertical cyclic loading response of geosynthetic-encased stone column in soft clay

Dynamic responses of the geosynthetic-encased stone column (GESC) supported embankment under traffic loads have become a hot topic. This study investigates the responses of GESC improved ground under vertical cyclic loading. A series of laboratory tests in a designed model test tank have been carried out with different loading parameters (varied loading amplitudes and frequencies), different column dimensions (varied encasement lengths and column diameters). In the tests, the soil-column stress distribution, accumulated settlement of loading plate, excess pore water pressure in the surrounding soil and lateral bulging of the stone column are monitored. Experimental results indicate that the vertical stress on the stone column increases with the increment of encasement length, and decreases with the increment of column diameter, loading amplitude and loading frequency. The increasing stress on the surrounding soil leads to a greater accumulated settlement of the loading plate and excess pore water pressure, while the increasing stress on the column leads to larger lateral bulging of the column. Excess pore water pressure dissipates effectively through vertical and horizontal drainage channels provided by the stone column and the sand bed. The geosynthetic encasement prevents the clay from obstructing the drainage channel by filtration and guarantees the drainage effect.     

Control Model for Large‐Sized Gantry Type Linear Motor Slider

At present, many industrial carrier devices utilize linear motor sliders. However, a heavier load requires a linear motor (which is an example of a direct drive device) to get higher power, compared with a rotary motor with a ball screw slider (which is an example of an indirect drive device). In order to obtain higher power at a lower cost, a linear slider with multiple motors can be utilized, for example, a gantry type linear motor slider. Moving the gantry type slider requires two linear motors that are set up in parallel to enable synchronization control. Some conventional synchronization control methods have been proposed for the parallel twin linear slider; however, a large‐scaled gantry type linear motor slider has two unique problems: mechanical distortion caused by the limitations of installation environment and coupling caused by joints with low stiffness. This paper proposes a control model to solve these problems, and an identification method of each parameter. Furthermore, the effectiveness of the control model is verified by comparison with simulation results and experimental results.     

Pluronic lecithin organogel of 5-aminosalicylic acid for wound healing

5-Aminosalicylic acid (5-ASA) is an aminosalicylate anti-inflammatory drug, which is also known as mesalazine or mesalamine. Currently employed in treating inflammatory bowel disease, ulcerative colitis, inflamed anus or rectum, and maintain remission in Crohn's disease. Evidence from the researchers highlighted its significant re-epithelization in allergic asthma, aphthous, and gastric ulcerative conditions. The objective of the study was to formulate the pluronic lecithin organogel (PLO) containing 5-ASA and evaluate its wound-healing ability in a full thickness excision wound rat model. The data obtained from in silico docking studies revealed 5-ASA is having an affinity towards the transforming growth factor-beta (TGF-β) specifically towards beta1. Among various formulations prepared (F1 to F8), F1, and F6 have shown a maximum in vitro drug release with optimum pH and viscosity. From MTT assay it was found that selected PLO formulations showed no toxicity and enhanced cell proliferation in HaCaT cell lines. In vivo wound-healing studies in albino Wistar rats has revealed that PLO accelerates wound closure and reepithelization to the statistically significant level on day 3 (p?相似文献   

Computing approximate blocking probabilities for transparent waveband switching based WDM networks using hierarchical cross-connects

An analytical model is presented to study the dynamics of wavelength division multiplexing (WDM) networks with waveband switching (WBS). The reduced load approximation method is considered to compute approximated network blocking probabilities in WBS-based WDM networks. The analytical model considers the link blocking probability due to insufficient link capacity and an impact of the waveband granularity (G). The analytical model also considers the node blocking probability due to unavailability of a switch port at the wavelength cross connect (WXC) layer of an Hierarchical cross connect (HXC) switch node. The set of nonlinear equations is obtained with the link independence assumption and solved using repeated substitutions. The accuracy of the analytical model is examined by comparing with simulation results considering the random-fit algorithm for waveband and wavelength assignments in different network scenarios. Lightpaths are routed between source and destination (s-d) HXC switch nodes using shortest path first (SPF) routing. An impact of the switch parameter to limit the input and the output WXC switch ports of an HXC switching node is also being investigated using the analytical model as well as through simulation results.     

基于Faster R-CNN的颜色导向火焰检测

基于深度特征的目标检测方法Faster R-CNN在火焰检测任务上存在检测效率低的问题,因此提出了基于颜色引导的抛锚策略。该策略设计火焰颜色模型来限制锚的生成,即利用火焰颜色约束锚的生成区域,从而减少了初始锚的数量,提升了计算效率。为了进一步提高网络的计算效率,将区域生成网络中的卷积层替换成掩膜卷积。为了验证所提方法的检测效果,采用BoWFire和Corsician数据集进行验证。实验结果表明,该方法实际检测速度相较于原Faster R-CNN提高了10.1%,BoWFire上该方法的火焰检测F值为0.87,Corsician上该方法的准确度可达99.33%。所提方法可以提高火焰检测的效率,并能够准确检测图像中的火焰。     

The thermodynamic characteristics of a Stirling/pulse tube hybrid cryocooler

A Stirling/pulse tube hybrid cryocooler (SPC), comprised of a Stirling cryocooler as the first stage and a pulse tube cryocooler as the second stage, features the ability of shifting cooling capacity between stages by adjusting the movement of the displacer in the first stage. Such an ability allows an SPC to accommodate itself to time-varying heat loads at different temperatures, which makes it a competitive candidate in space applications. However, due to the gas coupling, there exists a significant mutual effect between stages which endows an SPC with special thermodynamic characteristics and has a significant effect on the SPC’s capability of shifting cooling capacity between stages. With the phasor analysis and the thermodynamic analysis, this paper establishes an idealized model of an SPC. The model is then used to study the effect of the second stage on the first stage and reveal the condition that an SPC is able to shift cooling capacity between stages. Also, the model is compared with a Sage numerical model and the two models are consistent on the overall trend. Though it is unable to reflect reality precisely, the idealized model can interpret the mechanism and highlight some of the essential nature of an SPC, which will eventually benefit the appropriate design of an SPC.     

济阳坳陷下古生界潜山油气藏特征及成藏模式

济阳坳陷下古生界潜山具有多样性、复杂性的特点，潜山差异性的形成演化、油气成藏主控因素和控藏模式不明确，严重制约了该区潜山油气勘探。在潜山分类的基础上，综合利用系统恢复、分类对比和典型解剖等方法，揭示了济阳坳陷下古生界不同类型潜山的形成演化过程和油气成藏主控因素差异性，分类建立了油气成藏模式。研究表明，济阳坳陷下古生界主要发育高位新盖侵蚀残丘潜山、中位古盖拉张断块潜山、中位新古盖拉张剪切断块潜山、中位中古盖挤压拉张断块潜山和低位古盖拉张滑脱断块潜山5种潜山类型。不同类型潜山的形成演化和油气成藏各具特色，其中，高位新盖侵蚀残丘潜山的发育受隆升、侵蚀作用控制，油气成藏主要受控于油源和盖层条件，表现为"单向供烃、砂体-不整合岩溶体联合输导、残丘控藏"的成藏模式；中位古盖拉张断块潜山的发育受掀斜、断裂作用控制，油气成藏主要受控于储集条件，表现为"单向供烃、顺向断层输导、反向断层控藏"的成藏模式；中位新古盖拉张剪切断块潜山的发育受反转、翘倾和走滑切割作用控制，油气成藏主要受控于输导条件，表现为"多源供烃、断溶体立体输导、断裂控藏"的成藏模式；中位中古盖挤压拉张断块潜山的形成受强烈挤压、拉张滑脱作用控制，油气成藏主要受控于储集条件，表现为"多源供烃、断缝体输导、断褶控藏"的成藏模式；低位古盖拉张滑脱断块潜山的形成受强烈拉张滑脱作用控制，油气成藏主要受控于输导条件，表现为"顶部供烃、断缝体输导、断裂控藏"的成藏模式。     

Sarcopenia: Molecular Pathways and Potential Targets for Intervention

Aging is associated with sarcopenia. The loss of strength results in decreased muscle mass and motor function. This process accelerates the progressive muscle deterioration observed in older adults, favoring the presence of debilitating pathologies. In addition, sarcopenia leads to a decrease in quality of life, significantly affecting self-sufficiency. Altogether, these results in an increase in economic resources from the National Health Systems devoted to mitigating this problem in the elderly, particularly in developed countries. Different etiological determinants are involved in the progression of the disease, including: neurological factors, endocrine alterations, as well as nutritional and lifestyle changes related to the adoption of more sedentary habits. Molecular and cellular mechanisms have not been clearly characterized, resulting in the absence of an effective treatment for sarcopenia. Nevertheless, physical activity seems to be the sole strategy to delay sarcopenia and its symptoms. The present review intends to bring together the data explaining how physical activity modulates at a molecular and cellular level all factors that predispose or favor the progression of this deteriorating pathology.